PREVALENCE OF DYSLIPIDEMIA IN CHRONIC KIDNEY DISEASE PATIENTS
Keywords:
Chronic kidney disease; Dyslipidemia; Hypertriglyceridemia; HDL cholesterol; LDL cholesterol; Cardiovascular risk; Lipid profileAbstract
Background: Dyslipidemia is common in chronic kidney disease (CKD) and contributes to the high cardiovascular risk observed in this population. The pattern may differ from that seen in the general population, with triglyceride-rich lipoproteins and reduced high-density lipoprotein cholesterol frequently predominating.
Objective: To determine the frequency and pattern of dyslipidemia among adults with CKD presenting to a tertiary-care medical centre.
Methodology: This descriptive cross-sectional sample manuscript uses dataset representing 125 consecutive adults with CKD stages 3-5 who attended the medical outpatient department or were admitted to Islamabad Medical Complex (NESCOM), Islamabad, from January 2025 to June 2025. A fasting lipid profile was recorded, and dyslipidemia was defined as the presence of at least one abnormal lipid parameter.
Results: Dyslipidemia was observed in 89 of 125 patients (71.2%). Hypertriglyceridemia was the most frequent abnormality (57.6%), followed by low HDL-C (52.0%), high LDL-C (40.0%), and raised total cholesterol (32.8%). The frequency increased from 59.0% in stage 3 to 77.1% in stage 4 and 76.3% in stage 5 CKD.
Conclusion: Dyslipidemia was frequent in this CKD cohort, particularly among patients with more advanced disease. Lipid assessment should form part of cardiovascular-risk evaluation in CKD.
