Cosmetic Contact Lens-Related Eye Infection Associated with Irreversible Monocular Vision Loss: A Contemporary Clinical Case Report

Abstract

Cosmetic contact lenses (CCLs), also known as beauty or aesthetic lenses, are increasingly popular for altering eye color and enhancing appearance without the need for refractive correction. However, inappropriate use and poor hygiene practices may result in severe ocular morbidity. We present the case of a 28-year-old female healthcare professional who developed culture-negative keratitis with hypopyon after prolonged CCL wear and documented hygiene noncompliance. Despite the early administration of broad-spectrum antimicrobial therapy, the condition deteriorated rapidly, culminating in irreversible monocular vision loss with no light perception. Although microbiological findings were negative, the clinical profile was strongly suggestive of Acanthamoeba keratitis. A therapeutic tarsorrhaphy successfully reduced intraocular inflammation but was insufficient to restore corneal function or visual capacity.

This contemporary case highlights the preventable, vision-threatening complications of CCL misuse. It emphasizes diagnostic challenges in culture-negative keratitis, the potential role of Acanthamoeba infection, and the importance of public education, strict regulation, and sustainable preventive strategies.