2026. Title: Breast Cancer Is Globally Emerging Challenging: Epidemiology, Pathogensis and Therapeutic Approach (Enzymatic and Non-Enzymatic Antioxidant) –A Review. Pakistan Journal of Medical & Cardiological Review. 5, 2 (Apr. 2026), 566–587. DOI:https://doi.org/10.66021/pakmcr853.