EVALUATION OF RENAL CORTICAL ECHOGENICITY AND SERUM CREATININE CORRELATION ACROSS YOUNG AND ELDERLY GROUPS IN CKD PATIENTS
DOI:
https://doi.org/10.66021/pakmcr950Keywords:
Renal Cortical Echogenicity, Chronic Kidney Disease, Serum Creatinine, Ultrasound, Young and Elderly Groups, Renal FunctionAbstract
Background: Chronic Kidney Disease (CKD) is a progressive disease that is typified by structural and functional impairment of kidney. A non-invasive indicator of renal damage is renal cortical echogenicity on ultrasound and can be related to serum creatinine. It could be compared in different age groups with these parameters and it would help in the more efficient evaluation of the severity of the disease.
Methodology: A cross-sectional study was achieved on 94 CKD patients that received renal ultrasound and a serum creatinine test. The echogenicity of the cortex was marked using ultrasound and the demographic and clinical information was recorded in a structured form. The statistical analysis was carried out using SPSS, Chi-square test and T-tests was applied.
Aim of the study: To determine the correlation between renal cortical echogenicity, serum creatinine across groups between young and aged in CKD patients.
Results: The elderly had an even slightly higher level of serum creatinine and echogenicity grade compared to the young group. Echogenicity Grade between the Young and Elderly groups has a p-value of 0.052, which is slightly significant. The relationship between Echogenicity Grade and Age Group is marginally significant with the Elderly group presenting higher Echogenicity Grades, which points to a higher level of renal damage. Nevertheless, the difference in creatinine was not significant (p = 0.087) and the grade of echogenicity showed weak correlations with the age (p ≈ 0.05). There was no significant difference in the size of kidneys between groups.
Conclusion: The CKD patients under the age of 70 years are older with a higher renal cortical echogenicity and a worse structural destruction. Although there was a moderate increase in the levels of serum creatinine in the elderly patients, this was not significant. Non-invasive techniques of assessing renal damage like ultrasound are still advantageous.
