The Effects of Oxytocin on Blood Pressure and Heart Rate in Cesarean Section Patient Undergoing Spinal Anesthesia Students of Sarhad University Peshawar

Abstract

This research was conducted to evaluate the effect of oxytocin on blood pressure and heart rate in patients undergoing cesarean section under spinal anesthesia. Oxytocin is commonly used after delivery to help contract the uterus and prevent bleeding, but it can also cause significant cardiovascular changes. In this study, 60 patients were selected and divided into three age groups: 18–25, 26–35, and 36–45 years. Blood pressure and heart rate were recorded before and after the administration of oxytocin.

The findings revealed that oxytocin led to a decrease in systolic blood pressure in all age groups, with the greatest reduction seen in the 18–25 age group. The average systolic blood pressure dropped from 120 mmHg to 115 mmHg overall, with a statistically significant p-value of 0.03. The heart rate increased in all age groups after oxytocin use, with the average heart rate rising from 81 bpm to 89 bpm overall, which was also statistically significant (p=0.002).

These results indicate that oxytocin has a notable impact on cardiovascular function during cesarean delivery, especially in younger patients. It is important for anesthesiologists and obstetricians to be aware of these effects to ensure the safe use of oxytocin, particularly in patients who may be sensitive to blood pressure or heart rate changes. This study highlights the importance of careful monitoring during and after oxytocin administration in cesarean section cases.