SYNTHESIS AND BIOLOGICAL EVALUATION OF TRANSITION METAL COMPLEXES OF PYRAZOLE SCHIFF BASE LIGAND

Abstract

Pyrazole is the main component of bioactive agents, which act as antimicrobial, anti- inflammatory, analgesic, anticonvulsant, antibacterial, anxiolytic and antiviral agent. Pyrazole derivatives are also being used as therapeutic drugs which act on central nervous system (CNS). Azomethine derivatives of pyrazole also have biological potential and used as ligand to prepare metal complexes. Keeping the mentioned importance in view, in this research, we use amino pyrazole schiff base as ligand to prepare their metal complexes. The formation of products was monitored by using TLC, and the characterization of target compound has been done by melting point and FT-IR analysis. Antibacterial activity of these derivatives has also been studied.