Impact of Diverse intensities of acute exercise on Lipid Profiles and Cardiorespiratory Fitness in Prediabetic Populations Postprandially

Abstract

Background: The sedentary lifestyle common in modern society significantly contributes to various metabolic disorders, including prediabetes and dyslipidemia. Physical activity is known to influence metabolic health, but the effects of different exercise intensities on lipid profiles and cardiorespiratory fitness, particularly in prediabetic individuals, remain to be fully understood. This study aims to examine the impact of varying intensities of acute aerobic exercise on lipid profiles and cardiorespiratory fitness in a prediabetic population postprandially. Methods: A crossover study was conducted in 25 middle-aged, sedentary adults with prediabetes. Participants engaged in four sessions of anaerobic exercise at intensities of 50%, 60%, 70%, and 80% of their predicted maximum heart rate, with each session spaced one week apart. Lipid profiles were assessed at fasting, pre-exercise, and 30 and 60 minutes post-exercise. Results: The study demonstrated that acute aerobic exercise at higher intensities significantly improved lipid metabolism, evidenced by decreases in total cholesterol and triglycerides, and increases in high-density lipoprotein (HDL) across higher exercise intensities. Low-density lipoprotein (LDL) showed a slight decrease that became significant 60 minutes post-exercise at higher intensities. These changes suggest an intensity-dependent effect of exercise on lipid profiles. Conclusion: Acute aerobic exercise at varying intensities significantly affects lipid profiles in prediabetic individuals, in a dose response manner, with higher intensities yielding more pronounced benefits. This study supports the role of tailored exercise programs in managing prediabetes and associated metabolic risks, emphasizing the importance of exercise intensity in enhancing cardiovascular health and metabolic responses.