Clinical Analysis of Glycosylated Hemoglobin and Microalbuminuria in Initial Diagnosis of Renal Disease in Diabetic Male Patients
DOI:
https://doi.org/10.66021/pakmcr1431Keywords:
Type 2 diabetes mellitus, diabetic kidney disease, glycated hemoglobin, HbA1c, microalbuminuria, diabetic nephropathy, renal disease.Abstract
Background: Diabetic kidney disease (DKD) is a major microvascular complication of type 2 diabetes mellitus (T2DM), with microalbuminuria serving as one of the earliest clinical indicators of renal involvement. Poor glycemic control, reflected by elevated glycated hemoglobin (HbA1c), is strongly associated with the progression of diabetic nephropathy.
Objective: To evaluate the clinical relationship between HbA1c and microalbuminuria for the early detection of renal disease in diabetic male patients.
Methods: A cross-sectional comparative study was conducted among male patients with T2DM. Clinical and biochemical parameters, including age, HbA1c, and urinary microalbumin levels, were analyzed to determine their association with early renal impairment.
Results: Patients with poor glycemic control exhibited significantly higher urinary microalbumin levels, indicating an increased risk of early diabetic kidney disease. Elevated HbA1c was positively associated with microalbuminuria, supporting its role as an important predictor of renal dysfunction in diabetic patients.
Conclusion: HbA1c and microalbuminuria are valuable complementary biomarkers for the early clinical detection of diabetic renal disease. Routine assessment of these parameters may facilitate timely diagnosis, risk stratification, and early intervention to reduce the progression of diabetic nephropathy in male patients.
