A Comparative Study On The Effects Of Thyroid Gland Among The Females Of Different Age Groups From Hyderabad And Its Adjoining Areas
DOI:
https://doi.org/10.66021/pakmcr1123Keywords:
Incineration, Hospital Waste Management, Environmental Health, Healthcare Design, Indigenous DesignAbstract
The thyroid gland is a ductless endocrine gland located just below the larynx and in front of the trachea (windpipe). The main thyroid hormones are tetra-iodothyronine/thyroxin (T4) and tri-iodothyronine (T3). This study analyzed the effects of region, sex, and race on thyroxin (T4), tri-iodothyronine (T3), and thyroid-stimulating hormone (TSH) levels among women of different age groups. Serum T4, T3 and TSH levels were studied in 105 normal and healthy women in and around Hyderabad region. Serum T4 and T3 were analyzed by RIA (Radio-Immuno-Analysis) technique, while TSH was evaluated by IRMA (Immuno-radio-metric Assay) technique.
The results show that hormonal profiles were determined in a total of 105 patients. 40% of them belong to the age group of 10-35 years and 60% to the age group of 36-65 years. Respondents were further divided by region (city and countryside). In the age group 10-35, 57.14% and 42.86% of the respondents belonged to urban and rural areas. In the age group 36-65, 61.90% and 38.10% of the respondents belonged to urban and rural areas. Mean ± SEM for TSH, T3 and T4 in women aged 10-35 years were 3.00±0.65 µU/mL, 1.74±0.25 ng/mL, and 9.83±0.89 µg/mL. Mean ± SEM for TSH, T3 and T4 in women aged 36-65 years were 7.94±2.14 µU/mL, 2.39±0.26 ng/mL, and 10.98±0.78 µg/mL. The mean ± SEM of TSH, T3 and T4 in the age group of women of 10-35 years in the urban period was 2.93±0.86 µU/ml, 1.77±0.36 ng/ml and 10.35±1.34 µg/ml. Mean ± SEM of TSH, T3 and T4 in rural women aged 10-35 years were 3.09±0.99 µU/ml, 1.69±0.32 ng/ml, and 9.23±1.07 µg/ml. Mean ± SEM of TSH, T3 and T4 in urban women aged 36-65 years were 10.96±3.35 µU/ml, 1.72±0.20 ng/ml, and 10.08±0.93 µg/ml. Mean ± SEM of TSH, T3 and T4 in rural women aged 36-65 years were 2.99±0.79 µU/mL, 3.49±0.53 ng/mL, and 12.44±1.34 µg/mL. The levels of these hormones show a change in reference values used in clinical laboratories in Pakistan. Age has been found to significantly affect TSH, T3 and T4 levels.
