Valvular Calcification Burden in End-Stage Renal Disease: A Cross-Sectional Study from a Tertiary Care Center in Lahore
DOI:
https://doi.org/10.66021/pakmcr1118Keywords:
End-stage renal disease (ESRD), Aortic valve calcification, Mitral valve calcification, Hemodialysis, Echocardiography.Abstract
Background and Objective: Valvular calcification is a significant cardiovascular complication in patients with end-stage renal disease (ESRD), yet local data regarding its prevalence remain scarce.To determine the frequency of mitral valve calcification (MVC) and aortic valve calcification (AVC) in patients with ESRD on maintenance hemodialysis.
Study Design: Cross-sectional survey.
Setting: Department of Cardiology, Jinnah Hospital, Lahore.
Subjects & Methods: A total of 140 patients (both genders) diagnosed with ESRD for at least three months and undergoing maintenance hemodialysis were enrolled. Demographic data, including age, gender, and duration of ESRD, were recorded. Transthoracic echocardiography was performed on all subjects to identify the presence of MVC and AVC.
Results: The mean age of the study population was $39.24 \pm 11.31$ years. The cohort consisted of 89 (63.6%) males and 51 (36.4%) females. MVC was detected in 43 patients (30.7%), while AVC was present in 44 patients (31.4%). While gender and the duration of ESRD did not show a significant correlation with calcification, advancing age was significantly associated with the presence of both MVC and AVC ($p < 0.05$).
Conclusion: There is a high prevalence of mitral and aortic valve calcification among ESRD patients in our population. Given the associated cardiovascular risks, aggressive preventive strategies and regular echocardiographic screening are warranted in this high-risk group.
